Across TCGA patient cohorts, OR2B3 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2B3-associated genes across cancer lineages are Annexin-1, Caspase-7-cleavedD198, and c-Jun_pS73. Each is linked with OR2B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2B3-to-partner and partner-to-OR2B3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2B3→partner) and Y-score (partner→OR2B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.479	+3.169	.020	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.739	+2.584	.001	.010	3	2
UCEC	c-Jun_pS73 →	-0.135	-2.308	.031	.033	3	2
UCEC	14-3-3_beta →	-0.104	-2.432	.008	.018	3	1
UCEC	EGFR_pY1068 →	-0.260	-2.502	.008	.002	3	1
UCEC	FoxM1 →	+0.225	+1.584	.026	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

OR2B3 survival (RNA) · tumor vs normal (RNA) · all OR2B3 data types