OR2B2

Across TCGA pan-cancer cohorts, OR2B2 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2B2 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher OR2B2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2B2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

LIHC, PRAD, and UCEC are the cancer types where OR2B2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.144	0.688	.013	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	DFS	Median	All	0.956	0.632	.029	6	view →
SKCM	OS	Median	II,III,IV	1.000	0.294	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR2B2–LIHC (OS)

Open the LIHC breakdown →