OR2AT1P

Across TCGA patient cohorts, OR2AT1P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,752 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR2AT1P-associated GO terms across cancer lineages are Lysosomal lumen acidification, Reactive oxygen species metabolic process, and Respiratory burst. Each is linked with OR2AT1P in more than 15 cancer types. Because this analysis shows association rather than direction, both OR2AT1P-to-partner and partner-to-OR2AT1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal lumen acidification grouped by OR2AT1P-low versus OR2AT1P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AT1P→partner) and Y-score (partner→OR2AT1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Lysosomal lumen acidification →	+0.061	+0.192	<.001	<.001	3	16
STAD	Reactive oxygen species metabolic process →	+0.056	+0.190	<.001	<.001	3	15
ESCA	Respiratory burst →	+0.064	+0.201	<.001	<.001	3	14
STAD	Superoxide metabolic process →	+0.046	+0.143	<.001	<.001	3	14
STAD	Oxidative phosphorylation →	+0.071	+0.172	<.001	<.001	3	13
ESCA	Cellular oxidant detoxification →	+0.058	+0.176	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,752 associations by consensus.

Lysosomal lumen acidification by OR2AT1P expression — ESCA

Explore this box plot interactively →