Across TCGA pan-cancer cohorts, OR2AS1P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of OR2AS1P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR2AS1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR2AS1P is over-expressed in tumor.
KIRC are the cancer types where OR2AS1P tumor–normal differential expression is most reproducible.