OR2AM1P

Across TCGA pan-cancer cohorts, OR2AM1P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR2AM1P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR2AM1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR2AM1P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and COAD are the cancer types where OR2AM1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2AM1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.059	<.001	7	view →
BRCA	Female	All	−0.085	<.001	4	view →
COAD	All	All	−0.078	<.001	4	view →
LUAD	Female	All	−0.047	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

OR2AM1P–LUSC

Open the LUSC breakdown →