OR2AL1P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR2AL1P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR2AL1P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher OR2AL1P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR2AL1P expression acts as an unfavorable survival marker.

SKCM, STAD, and TGCT are the cancer types where OR2AL1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileAll0.0630.731<.00199view →
STADOSTertileIII,IV0.1730.557<.00154view →
TGCTDFSTertileII,III,IV0.0150.919<.00154view →
THCADFSTertileII,III,IV0.1450.794.00136view →
ACCDFSTertileII,III,IV0.2420.724.03418view →
ESCADFSTertileII,III,IV0.1310.776.0439view →
LGGDFSTertileAll0.2240.728.0259view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR2AL1P–SKCM (DFS)

Kaplan–Meier survival curve for OR2AL1P RNA-high vs -low samples in SKCM.

Open the SKCM breakdown →

Exploration