OR2AJ1

Across TCGA cell cohorts, OR2AJ1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2AJ1-associated genes across cancer lineages are PTH, OR4N5, and IQCF3. Each is linked with OR2AJ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AJ1-to-partner and partner-to-OR2AJ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by OR2AJ1-low versus OR2AJ1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AJ1→partner) and Y-score (partner→OR2AJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PTH →	+0.027	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4N5 →	+0.012	+5.662	.004	.002	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.028	+5.228	<.001	.005	3	1
LUNG_SCLC	RTL3 →	+0.270	+3.817	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PTH by OR2AJ1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →