Across TCGA patient cohorts, OR2AG2 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2AG2-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and EGFR. Each is linked with OR2AG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AG2-to-partner and partner-to-OR2AG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AG2→partner) and Y-score (partner→OR2AG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.091	-2.295	.020	.033	3	1
UCEC	EGFR_pY1068 →	-0.276	-2.807	.005	.003	3	1
UCEC	EGFR →	-0.175	-2.000	.005	.010	3	1
UCEC	A-Raf_pS299 →	-0.155	-3.700	<.001	.001	3	1
UCEC	ERK2 →	+0.169	+2.000	.025	.030	3	1
UCEC	Gab2 →	+0.346	+1.584	.013	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

OR2AG2 survival (RNA) · tumor vs normal (RNA) · all OR2AG2 data types