OR2AG1

Across TCGA patient cohorts, OR2AG1 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2AG1-associated genes across cancer lineages are PRAS40_pT246, Rab11, and STAT3_pY705. Each is linked with OR2AG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2AG1-to-partner and partner-to-OR2AG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAS40_pT246 grouped by OR2AG1-low versus OR2AG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AG1→partner) and Y-score (partner→OR2AG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAS40_pT246 →	+0.216	+2.183	.016	.035	3	1
UCEC	Rab11 →	-0.209	-3.150	.005	.019	3	1
UCEC	STAT3_pY705 →	-0.517	-3.321	<.001	.010	3	1
UCEC	p21 →	+0.226	+3.000	.025	.036	2	1
UCEC	p62 Lck ligand →	+0.618	+3.321	<.001	.010	2	1
UCEC	Rab25 →	-0.593	-3.321	<.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PRAS40_pT246 by OR2AG1 expression — UCEC

Explore this box plot interactively →