OR2AG1

Across TCGA cell cohorts, OR2AG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 921 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR2AG1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, mRNA cis splicing, via spliceosome, and Regulation of mRNA splicing, via spliceosome. Each is linked with OR2AG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OR2AG1-to-partner and partner-to-OR2AG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by OR2AG1-low versus OR2AG1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2AG1→partner) and Y-score (partner→OR2AG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of DNA-templated transcription, elongation →	+0.051	+0.048	.003	.002	3	6
BLOOD_Leukemia	mRNA cis splicing, via spliceosome →	+0.035	+0.040	.008	.008	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.076	+0.023	<.001	.008	3	5
LARGE_INTESTINE	Synaptic transmission, cholinergic →	-0.103	-0.016	.001	.008	3	5
PANCREAS	miRNA metabolic process →	+0.077	+0.015	.003	.001	3	5
BLOOD_Leukemia	Positive regulation of viral process →	+0.037	+0.040	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 921 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by OR2AG1 expression — BLOOD_Myeloma

Explore this box plot interactively →