OR2AE1

Across TCGA pan-cancer cohorts, OR2AE1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR2AE1 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher OR2AE1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2AE1 expression acts as an unfavorable survival marker.

ESCA, LUAD, and LIHC are the cancer types where OR2AE1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.080	0.701	<.001	12	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	6	view →
LIHC	DFS	Median	All	0.034	0.554	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

OR2AE1–ESCA (OS)

Open the ESCA breakdown →