OR2A7

Across TCGA pan-cancer cohorts, OR2A7 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated OR2A7 data layer compared with 3 for mutation status.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher OR2A7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated OR2A7 expression acts as an unfavorable survival marker, although some lineages such as READ and MESO show a favorable association.

READ, MESO, and DLBC are the cancer types where OR2A7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Quartile	III,IV	0.906	0.596	.002	50	view →
MESO	OS	Median	All	0.694	0.423	<.001	45	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.008	34	view →
ESCA	DFS	Median	All	1.000	0.336	.003	32	view →
LAML	DFS	Quartile	All	0.417	0.718	.002	28	view →
SCLC	DFS	Quartile	II,III,IV	0.548	0.152	.005	24	view →
LGG	DFS	Quartile	All	0.578	0.785	<.001	20	view →
KIRC	DFS	Quartile	III,IV	0.821	0.636	.013	19	view →
BRCA	OS	Tertile	IV	0.989	0.577	.033	12	view →
ACC	DFS	Tertile	All	0.764	0.244	.003	12	view →
UCS	OS	Median	IV	0.673	0.248	.033	12	view →
LUAD	OS	Tertile	All	0.544	0.289	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

OR2A7–READ (OS)

Open the READ breakdown →