OR2A7

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR2A7 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR2A7 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR2A7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2A7 expression acts as an unfavorable survival marker.

COAD, DLBC, and UCEC are the cancer types where OR2A7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianAll0.1680.799.00418view →
DLBCOSMedianAll0.0540.842<.00112view →
UCECOSMedianAll0.1280.679.01710view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

OR2A7–COAD (OS)

Kaplan–Meier survival curve for OR2A7 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration