Across TCGA cell cohorts, OR2A5 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR2A5-associated genes across cancer lineages are HMHB1, TPPP2, and CDR1. Each is linked with OR2A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A5-to-partner and partner-to-OR2A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A5→partner) and Y-score (partner→OR2A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HMHB1 →	+0.032	+3.700	<.001	.009	3	1
SKIN	TPPP2 →	+0.048	+3.217	<.001	.006	3	1
SKIN	CDR1 →	+0.145	+3.242	.009	.003	3	1
SKIN	BPIFB3 →	+0.012	+3.700	<.001	.009	3	1
LUNG_NSCLC_LUAD	SPINT4 →	+0.036	+4.228	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PNLIP →	+0.003	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

OR2A5 survival (RNA) · tumor vs normal (RNA) · all OR2A5 data types