OR2A15P

Across TCGA pan-cancer cohorts, OR2A15P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated OR2A15P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR2A15P RNA is associated with better overall survival. In most high-consensus cancer types, elevated OR2A15P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, MESO, and CHOL are the cancer types where OR2A15P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.928	0.727	.006	102	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
CHOL	OS	Tertile	II,III,IV	0.140	0.748	<.001	54	view →
KIRC	DFS	Tertile	IV	0.172	0.386	.003	42	view →
LUAD	DFS	Tertile	IV	0.357	0.710	.019	18	view →
UCEC	DFS	Tertile	All	0.715	0.845	.025	18	view →
READ	DFS	Tertile	III,IV	0.179	0.767	<.001	18	view →
LUSC	DFS	Tertile	All	0.654	0.770	.012	15	view →
TGCT	DFS	Tertile	All	0.403	0.841	.014	12	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
THCA	OS	Tertile	All	0.961	0.989	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

OR2A15P–HNSC (OS)

Open the HNSC breakdown →