Across TCGA patient cohorts, OR1S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,899 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR1S2-associated GO terms across cancer lineages are Positive regulation of DNA-templated transcription initiation, Positive regulation of G1/S transition of mitotic cell cycle, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with OR1S2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR1S2-to-partner and partner-to-OR1S2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1S2→partner) and Y-score (partner→OR1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA-templated transcription initiation →	+0.134	+0.039	<.001	<.001	3	5
ESCA	Positive regulation of G1/S transition of mitotic cell cycle →	+0.116	+0.035	<.001	.004	3	5
STAD	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.094	+0.072	<.001	<.001	3	5
ESCA	Positive regulation of telomere maintenance via telomere lengthening →	+0.150	+0.035	<.001	.001	3	5
ESCA	DNA integrity checkpoint signaling →	+0.149	+0.039	<.001	.001	3	5
ESCA	Maintenance of sister chromatid cohesion →	+0.136	+0.026	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,899 associations by consensus.

Exploration

OR1S2 survival (RNA) · tumor vs normal (RNA) · all OR1S2 data types