Across TCGA patient cohorts, OR1S2 mutation is significantly associated with the RNA expression of many other genes, with 1,266 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR1S2-associated genes across cancer lineages are RN7SKP113, RN7SL840P, and RPSAP35. Each is linked with OR1S2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR1S2-to-partner and partner-to-OR1S2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1S2→partner) and Y-score (partner→OR1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RN7SKP113 →	+0.205	+6.380	<.001	.001	3	3
LUAD	RN7SL840P →	+0.404	+3.105	<.001	.005	3	3
HNSC	RPSAP35 →	+0.061	+5.888	<.001	<.001	3	3
SKCM	LYSMD4 →	+0.437	+2.632	.001	.005	3	3
SCLC	C12orf40 →	+0.266	+4.169	<.001	.008	3	2
UCEC	NUDT4P2 →	+0.053	+2.899	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,266 associations by consensus.

Exploration

OR1S2 survival (RNA) · tumor vs normal (RNA) · all OR1S2 data types