Across TCGA patient cohorts, OR1S2 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1S2-associated genes across cancer lineages are Platelets, mv Endothelial cells, and pDC. Each is linked with OR1S2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1S2-to-partner and partner-to-OR1S2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1S2→partner) and Y-score (partner→OR1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Platelets →	+0.016	+2.211	.015	.036	3	2
UCEC	mv Endothelial cells →	-0.023	-2.321	.022	.035	3	2
UCEC	pDC →	+0.056	+2.202	.007	.033	3	2
HNSC	CD4+ Tem →	+0.012	+5.038	<.001	.039	3	1
UCEC	Endothelial cells →	-0.037	-3.148	.024	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.023	-2.660	.028	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

OR1S2 survival (RNA) · tumor vs normal (RNA) · all OR1S2 data types