Across TCGA pan-cancer cohorts, OR1R1P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR1R1P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where OR1R1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR1R1P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KICH and LUSC are the cancer types where OR1R1P tumor–normal differential expression is most reproducible.