OR1N1

Across TCGA patient cohorts, OR1N1 mutation is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1N1-associated genes across cancer lineages are ATP5F1AP7, LINC02232, and RNA5SP113. Each is linked with OR1N1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1N1-to-partner and partner-to-OR1N1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5F1AP7 grouped by OR1N1-low versus OR1N1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1N1→partner) and Y-score (partner→OR1N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ATP5F1AP7 →	+0.094	+5.421	<.001	.005	3	2
READ	LINC02232 →	+0.027	+5.039	<.001	.008	3	2
BRCA	RNA5SP113 →	+0.306	+5.711	<.001	.001	3	2
BRCA	RN7SKP263 →	+0.113	+4.540	.001	.009	3	2
UCEC	TMEM138 →	+0.338	+3.595	.003	.001	3	2
UCEC	CLDND2 →	+0.770	+3.595	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

ATP5F1AP7 by OR1N1 expression — READ

Explore this box plot interactively →