OR1M1

Across TCGA pan-cancer cohorts, OR1M1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR1M1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR1M1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR1M1 is over-expressed in tumor, although a few such as LUSC and STAD show the opposite, repressed pattern.

LUSC, KIRC, and LUAD are the cancer types where OR1M1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR1M1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.018	.023	3	view →
KIRC	All	All	+0.005	.026	2	view →
LUAD	Female	All	+0.024	.023	1	view →
STAD	Male	II,III,IV	−0.017	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

OR1M1–LUSC

Open the LUSC breakdown →