OR1L4

Across TCGA cell cohorts, OR1L4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR1L4-associated genes across cancer lineages are OR11H1 and OR10W1. Each is linked with OR1L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1L4-to-partner and partner-to-OR1L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by OR1L4-low versus OR1L4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L4→partner) and Y-score (partner→OR1L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.045	+5.201	.002	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR11H1 by OR1L4 expression — BLOOD_Leukemia

Explore this box plot interactively →