OR1L1

Across TCGA cell cohorts, OR1L1 RNA expression is significantly associated with the mutation status of many other genes, with 134 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR1L1-associated genes across cancer lineages are DUOX1, DNAH6, and ASB10. Each is linked with OR1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1L1-to-partner and partner-to-OR1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUOX1 grouped by OR1L1-low versus OR1L1-high in BONE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1L1→partner) and Y-score (partner→OR1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DUOX1 →	+5.169	+0.033	.004	<.001	3	2
CNS	DNAH6 →	+2.639	+0.014	.005	<.001	3	2
OVARY	ASB10 →	+5.196	+0.022	.005	<.001	3	2
LUNG_SCLC	SEMG2 →	+5.029	+0.045	.006	<.001	3	2
LUNG_SCLC	MMP16 →	+3.029	+0.022	.003	<.001	3	2
BONE	OTOF →	+4.169	+0.025	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 134 associations by consensus.

DUOX1 by OR1L1 expression — BONE

Explore this box plot interactively →