OR1K1

Across TCGA patient cohorts, OR1K1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,676 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OR1K1-associated proteins across cancer lineages are SEPTIN4, ARHGEF6, and PTPA. Each is linked with OR1K1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR1K1-to-partner and partner-to-OR1K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OR1K1 versus SEPTIN4 in PDAC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1K1→partner) and Y-score (partner→OR1K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SEPTIN4 →	+0.410	+0.285	.003	.008	3	4
LSCC	ARHGEF6 →	+0.496	+0.361	<.001	.001	3	3
GBM	PTPA →	+0.305	+0.412	<.001	.001	3	3
CCRCC	RGCC →	+0.383	+0.344	.003	<.001	3	3
LSCC	LYL1_S260 →	+0.636	+0.442	<.001	<.001	3	3
PDAC	ARAF_S157 →	-0.329	-0.319	.007	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,676 associations by consensus.

OR1K1 vs SEPTIN4 — PDAC

Explore this scatter interactively →