OR1J2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR1J2 mutation is significantly associated with the RNA expression of many other genes, with 1,327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1J2-associated genes across cancer lineages are IGHD5-12, PCGF5, and STRN3. Each is linked with OR1J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1J2-to-partner and partner-to-OR1J2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1J2→partner) and Y-score (partner→OR1J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READIGHD5-12 →+1.287+4.421<.001.00932
SKCMPCGF5 →+0.578+2.006.001.00132
UCECSTRN3 →+0.619+3.343.007.00532
UCECASPH →+0.983+3.343.001.00532
UCECZNF805 →+0.528+3.218.007.00932
UCECRNU6-4P →+0.588+3.234.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,327 associations by consensus.

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