OR1J2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR1J2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1J2-associated genes across cancer lineages are Caspase-7-cleavedD198, SETD2, and CD49b. Each is linked with OR1J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1J2-to-partner and partner-to-OR1J2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1J2→partner) and Y-score (partner→OR1J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.745+2.827.022.03532
SKCMSETD2 →-0.143-2.700.025.00631
SKCMCD49b →+0.366+2.717<.001.00331
SKCM4E-BP1_pT70 →-0.241-2.683.002.00631
UCECRab25 →-0.463-3.169.010.02021
UCECVHL →-1.086-3.169.003.01921
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

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