Across TCGA patient cohorts, OR1G1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1G1-associated genes across cancer lineages are EGFR_pY1068, Myosin-IIa, and p62 Lck ligand. Each is linked with OR1G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1G1-to-partner and partner-to-OR1G1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1G1→partner) and Y-score (partner→OR1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.271	-2.999	.013	.035	3	1
UCEC	Myosin-IIa →	+0.240	+3.180	.005	.010	3	1
UCEC	p62 Lck ligand →	+0.372	+3.331	.008	.005	3	1
UCEC	PCNA →	+0.210	+2.999	.026	.035	3	1
UCEC	Annexin-1 →	+0.662	+3.479	.003	.002	3	1
UCEC	Di-Ras3 →	-0.128	-2.115	.048	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

OR1G1 survival (RNA) · tumor vs normal (RNA) · all OR1G1 data types