OR1D2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR1D2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR1D2-associated genes across cancer lineages are SERPINA7, DMRTB1, and OR4K1. Each is linked with OR1D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1D2-to-partner and partner-to-OR1D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1D2→partner) and Y-score (partner→OR1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADSERPINA7 →+0.006+5.228.005.00531
LUNG_NSCLC_LUADDMRTB1 →+0.006+4.887<.001.00931
LUNG_NSCLC_LUADOR4K1 →+0.019+5.228<.001.00531
LUNG_NSCLC_LUADOR1L3 →+0.028+4.887<.001.00931
LUNG_NSCLC_LUADOR13C8 →+0.036+5.662<.001.00231
LUNG_NSCLC_LUADLCE2C →+0.042+5.662<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration