Across TCGA cell cohorts, OR1D2 mutation is significantly associated with the mutation status of many other genes, with 1,336 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR1D2-associated genes across cancer lineages are TARS2, NTRK2, and EPHA8. Each is linked with OR1D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR1D2-to-partner and partner-to-OR1D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1D2→partner) and Y-score (partner→OR1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TARS2 →	+3.007	+3.584	.008	.008	1	3
PANCREAS	NTRK2 →	+5.115	+5.115	.005	.005	1	2
PANCREAS	EPHA8 →	+5.115	+5.115	.005	.005	1	2
LUNG_NSCLC_LUAD	KRT5 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	MAP3K5 →	+4.772	+5.339	.004	.004	1	2
LUNG_NSCLC_LUAD	ENPP1 →	+4.772	+5.339	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,336 associations by consensus.

Exploration

OR1D2 survival (RNA) · tumor vs normal (RNA) · all OR1D2 data types