Across TCGA patient cohorts, OR1C1 mutation is significantly associated with the RNA expression of many other genes, with 1,873 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR1C1-associated genes across cancer lineages are MIR4790, DTYMK, and CDC6. Each is linked with OR1C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR1C1-to-partner and partner-to-OR1C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1C1→partner) and Y-score (partner→OR1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4790 →	+0.392	+7.632	<.001	<.001	3	3
UCEC	DTYMK →	+0.512	+1.971	.003	.009	3	3
UCEC	CDC6 →	+0.821	+3.593	<.001	.001	3	3
UCEC	TIMM44 →	+0.403	+2.447	.002	.001	3	3
UCEC	NDUFAF1 →	+0.538	+2.425	<.001	.002	3	3
LUAD	PKMYT1 →	+0.596	+2.247	.007	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,873 associations by consensus.

Exploration

OR1C1 survival (RNA) · tumor vs normal (RNA) · all OR1C1 data types