Across TCGA pan-cancer cohorts, OR1AA1P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of OR1AA1P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR1AA1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR1AA1P is over-expressed in tumor.
LUSC are the cancer types where OR1AA1P tumor–normal differential expression is most reproducible.