OR1A2

Across TCGA patient cohorts, OR1A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,210 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR1A2-associated GO terms across cancer lineages are Regulation of DNA binding, Negative regulation of secretion, and Regulation of reproductive process. Each is linked with OR1A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both OR1A2-to-partner and partner-to-OR1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA binding grouped by OR1A2-low versus OR1A2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1A2→partner) and Y-score (partner→OR1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA binding →	+0.084	+0.124	<.001	<.001	3	9
STAD	Negative regulation of secretion →	+0.052	+0.095	<.001	<.001	3	8
STAD	Regulation of reproductive process →	+0.051	+0.112	<.001	<.001	3	7
STAD	Regulation of mitochondrion organization →	+0.091	+0.112	<.001	<.001	3	7
STAD	Positive regulation of T cell mediated immunity →	+0.068	+0.121	<.001	<.001	3	7
STAD	Receptor internalization →	+0.078	+0.112	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,210 associations by consensus.

Regulation of DNA binding by OR1A2 expression — STAD

Explore this box plot interactively →