OR1A2

Across TCGA cell cohorts, OR1A2 RNA expression is significantly associated with the mutation status of many other genes, with 77 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR1A2-associated genes across cancer lineages are CCDC114, CORO2A, and RPS6KB1. Each is linked with OR1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR1A2-to-partner and partner-to-OR1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC114 grouped by OR1A2-low versus OR1A2-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR1A2→partner) and Y-score (partner→OR1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCDC114 →	+4.266	+0.011	.004	<.001	3	1
LUNG_NSCLC_LUAD	CORO2A →	+6.266	+0.023	<.001	<.001	3	1
LUNG_NSCLC_LUAD	RPS6KB1 →	+6.266	+0.023	<.001	<.001	3	1
LUNG_NSCLC_LUAD	PLXNA1 →	+3.681	+0.008	.009	<.001	3	1
LUNG_NSCLC_LUAD	SLC5A9 →	+4.681	+0.014	.003	<.001	3	1
LUNG_NSCLC_LUAD	ATP10B →	+3.681	+0.008	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

CCDC114 by OR1A2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →