Across TCGA pan-cancer cohorts, OR14L1P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of OR14L1P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR14L1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR14L1P is over-expressed in tumor, although a few such as LUSC and BLCA show the opposite, repressed pattern.
LUSC, BLCA, and LUAD are the cancer types where OR14L1P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR14L1P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.