OR14J1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR14J1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR14J1-associated genes across cancer lineages are 14-3-3_epsilon, Acetyl-a-Tubulin-Lys40, and INPP4B. Each is linked with OR14J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14J1-to-partner and partner-to-OR14J1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14J1→partner) and Y-score (partner→OR14J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCM14-3-3_epsilon →+0.137+2.132.009.01032
UCECAcetyl-a-Tubulin-Lys40 →+0.502+2.459.041.02031
UCECINPP4B →-0.323-3.000.039.03631
UCECAnnexin-1 →+0.577+2.827.023.03531
UCECSTAT3_pY705 →-0.415-2.459.001.02031
UCECTuberin_pT1462 →+0.221+2.179.048.03431
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration