OR14A2

Across TCGA cell cohorts, OR14A2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR14A2-associated genes across cancer lineages are OR1L1, CSN3, and OR9I1. Each is linked with OR14A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14A2-to-partner and partner-to-OR14A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L1 grouped by OR14A2-low versus OR14A2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14A2→partner) and Y-score (partner→OR14A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR1L1 →	+0.052	+5.029	<.001	.006	3	1
SKIN	CSN3 →	+1.263	+3.920	<.001	.005	3	1
SKIN	OR9I1 →	+0.004	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR1L1 by OR14A2 expression — LUNG_SCLC

Explore this box plot interactively →