OR14A2

Across TCGA cell cohorts, OR14A2 mutation is significantly associated with the mutation status of many other genes, with 136 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR14A2-associated genes across cancer lineages are OR6N1, KIR2DL3, and LGALS16. Each is linked with OR14A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR14A2-to-partner and partner-to-OR14A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6N1 grouped by OR14A2-low versus OR14A2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR14A2→partner) and Y-score (partner→OR14A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6N1 →	+2.830	+3.548	.009	.009	1	2
SKIN	KIR2DL3 →	+5.053	+4.239	.007	.007	1	1
SKIN	LGALS16 →	+5.053	+4.239	.007	.007	1	1
SKIN	UBE2NL →	+5.053	+4.239	.007	.007	1	1
SKIN	USP15 →	+5.053	+4.239	.007	.007	1	1
SKIN	ECPAS →	+3.053	+3.718	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

OR6N1 by OR14A2 expression — SKIN

Explore this box plot interactively →