OR13J1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR13J1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated OR13J1 data layer compared with 1 for mutation status.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR13J1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR13J1 expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.

DLBC, KIRP, and CESC are the cancer types where OR13J1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSQuartileAll0.2071.000<.00151view →
KIRPDFSQuartileAll0.8150.951.00331view →
CESCDFSMedianIV0.5990.090.00230view →
THYMOSQuartileAll0.7541.000.00327view →
BLCAOSMedianIV0.2230.563.00624view →
UCECOSQuartileII,III,IV0.2810.791.00324view →
ESCAOSMedianIII,IV0.7310.437.00121view →
PRADDFSMedianAll0.8220.942<.00120view →
THCADFSQuartileII,III,IV0.6940.916.00218view →
LUSCDFSQuartileAll0.5530.679.01214view →
ACCDFSTertileII,III,IV0.2560.656.01711view →
SKCMDFSTertileII,III,IV0.4370.215.01110view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

OR13J1–DLBC (OS)

Kaplan–Meier survival curve for OR13J1 RNA-high vs -low samples in DLBC.

Open the DLBC breakdown →

Exploration