OR13F1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR13F1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13F1-associated genes across cancer lineages are eIF4E, TTF1, and YAP. Each is linked with OR13F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13F1-to-partner and partner-to-OR13F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13F1→partner) and Y-score (partner→OR13F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMeIF4E →+0.131+1.765.047.01332
LUADTTF1 →+0.974+3.321.035.01022
LUADYAP →+0.377+3.321<.001.01031
UCEC14-3-3_beta →-0.098-2.979.044.03631
UCECNotch1 →+0.141+3.009.038.01931
UCECSTAT3_pY705 →-0.478-2.459<.001.02031
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

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