OR13D1

Across TCGA cell cohorts, OR13D1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR13D1-associated genes across cancer lineages are METTL5, VSTM2B, and PEX3. Each is linked with OR13D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13D1-to-partner and partner-to-OR13D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL5 grouped by OR13D1-low versus OR13D1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13D1→partner) and Y-score (partner→OR13D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	METTL5 →	+0.369	+3.064	.003	.009	3	1
LARGE_INTESTINE	VSTM2B →	+0.041	+3.009	<.001	.001	3	1
LARGE_INTESTINE	PEX3 →	+0.712	+3.192	<.001	.007	3	1
LUNG_NSCLC_LUAD	MBD3L2 →	+0.151	+5.228	<.001	.005	3	1
SKIN	SLC22A7 →	+0.015	+3.700	<.001	.009	3	1
SKIN	HJV →	+0.029	+3.376	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

METTL5 by OR13D1 expression — LARGE_INTESTINE

Explore this box plot interactively →