OR13C9

Across TCGA patient cohorts, OR13C9 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13C9-associated genes across cancer lineages are FoxM1, Cyclin-B1, and MEK1. Each is linked with OR13C9 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C9-to-partner and partner-to-OR13C9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by OR13C9-low versus OR13C9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C9→partner) and Y-score (partner→OR13C9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FoxM1 →	+0.167	+1.906	.041	.016	3	2
SKCM	Cyclin-B1 →	+0.345	+1.749	.034	.049	3	2
UCEC	MEK1 →	+0.406	+2.584	.011	.010	3	2
UCEC	p62 Lck ligand →	+0.353	+3.331	.013	.005	3	2
UCEC	PRAS40_pT246 →	+0.166	+1.598	.027	.044	3	2
UCEC	Rb_pS807_S811 →	+0.451	+2.115	.010	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

FoxM1 by OR13C9 expression — SKCM

Explore this box plot interactively →