OR13C3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR13C3 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13C3-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, Notch1, and PCNA. Each is linked with OR13C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C3-to-partner and partner-to-OR13C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C3→partner) and Y-score (partner→OR13C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMAcetyl-a-Tubulin-Lys40 →+0.570+1.584.003.01832
UCECNotch1 →+0.170+3.331.002.00532
UCECPCNA →+0.306+2.415<.001.00332
UCECCyclin-B1 →+0.801+3.087<.001<.00132
UCECEGFR_pY1068 →-0.236-2.415.019.00331
UCECeIF4G →+0.340+3.169.006.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

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