OR13C2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR13C2 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR13C2-associated genes across cancer lineages are N-Cadherin, PDK1, and TAZ. Each is linked with OR13C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13C2-to-partner and partner-to-OR13C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Cadherin grouped by OR13C2-low versus OR13C2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13C2→partner) and Y-score (partner→OR13C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMN-Cadherin →+0.167+3.169.042.01832
SKCMPDK1 →-0.108-2.171.018.01031
SKCMTAZ →+0.201+2.334.002.01831
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

N-Cadherin by OR13C2 expression — SKCM

Box plot of N-Cadherin in OR13C2-low vs OR13C2-high samples in SKCM.

Explore this box plot interactively →

Exploration