OR13A1

Across TCGA patient cohorts, OR13A1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR13A1-associated genes across cancer lineages are GAPDH, HER2_pY1248, and mTOR_pS2448. Each is linked with OR13A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR13A1-to-partner and partner-to-OR13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by OR13A1-low versus OR13A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR13A1→partner) and Y-score (partner→OR13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.389	+1.874	.048	.049	3	2
UCEC	HER2_pY1248 →	-0.230	-3.392	.019	<.001	3	2
UCEC	mTOR_pS2448 →	-0.141	-2.209	.010	.009	3	2
UCEC	p27_pT198 →	+0.101	+1.502	.010	.030	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.396	-1.489	.016	.030	3	2
UCEC	Src_pY527 →	-0.342	-3.169	.030	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

GAPDH by OR13A1 expression — UCEC

Explore this box plot interactively →