OR11H12

Across TCGA patient cohorts, OR11H12 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR11H12-associated genes across cancer lineages are p62 Lck ligand, TFRC, and CD31. Each is linked with OR11H12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11H12-to-partner and partner-to-OR11H12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by OR11H12-low versus OR11H12-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11H12→partner) and Y-score (partner→OR11H12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	p62 Lck ligand →	+0.510	+2.594	.036	.006	3	2
LUSC	TFRC →	+0.645	+3.000	.025	.033	3	2
SKCM	CD31 →	-0.182	-3.459	.022	.005	3	2
LUSC	ER-alpha →	-0.192	-3.169	.024	.017	3	1
LUSC	MSH6 →	+0.473	+2.594	.005	.006	3	1
LUSC	VHL →	+0.755	+1.883	.035	.031	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

p62 Lck ligand by OR11H12 expression — LUSC

Explore this box plot interactively →