OR11H1

Across TCGA patient cohorts, OR11H1 mutation is significantly associated with the RNA expression of many other genes, with 2,276 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR11H1-associated genes across cancer lineages are ZNF598, ZNF778, and CDC34. Each is linked with OR11H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR11H1-to-partner and partner-to-OR11H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF598 grouped by OR11H1-low versus OR11H1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11H1→partner) and Y-score (partner→OR11H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF598 →	+0.503	+3.515	.002	.002	3	3
UCEC	ZNF778 →	+0.685	+2.756	<.001	.002	3	3
UCEC	CDC34 →	+0.436	+3.609	.005	.001	3	3
SKCM	NEDD4L →	+0.868	+3.106	.001	<.001	3	3
UCEC	MBOAT7 →	+0.485	+3.700	<.001	.001	3	3
UCEC	YTHDF1 →	+0.327	+3.032	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

ZNF598 by OR11H1 expression — UCEC

Explore this box plot interactively →