Across TCGA patient cohorts, OR11G2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR11G2-associated genes across cancer lineages are Shc_pY317, Caspase-8, and 14-3-3_beta. Each is linked with OR11G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR11G2-to-partner and partner-to-OR11G2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR11G2→partner) and Y-score (partner→OR11G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.215	-2.999	.002	.035	3	2
UCEC	Caspase-8 →	-0.272	-3.143	.020	.018	3	2
UCEC	14-3-3_beta →	-0.126	-2.973	.006	.035	3	1
UCEC	Heregulin →	-0.179	-2.986	.001	.035	3	1
UCEC	INPP4B →	-0.453	-3.459	.002	.005	3	1
UCEC	MSH2 →	-0.241	-2.973	.024	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

OR11G2 survival (RNA) · tumor vs normal (RNA) · all OR11G2 data types