Across TCGA patient cohorts, OR10Z1 mutation is significantly associated with the RNA expression of many other genes, with 1,303 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR10Z1-associated genes across cancer lineages are GTSE1, MIR454, and SMS. Each is linked with OR10Z1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR10Z1-to-partner and partner-to-OR10Z1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10Z1→partner) and Y-score (partner→OR10Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GTSE1 →	+0.497	+3.012	.003	<.001	3	4
BLCA	MIR454 →	+0.364	+2.844	<.001	.009	3	4
SKCM	SMS →	+0.536	+2.273	<.001	<.001	3	3
LUAD	OIP5 →	+0.852	+3.193	.001	.009	3	3
LUAD	FOXM1 →	+1.119	+2.700	.001	.006	3	3
SKCM	NEK2 →	+0.726	+2.266	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,303 associations by consensus.

Exploration

OR10Z1 survival (RNA) · tumor vs normal (RNA) · all OR10Z1 data types