OR10Z1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR10Z1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR10Z1-associated genes across cancer lineages are FoxM1, p38-MAPK_pT180_Y182, and FOXO3a_pS318_S321. Each is linked with OR10Z1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10Z1-to-partner and partner-to-OR10Z1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10Z1→partner) and Y-score (partner→OR10Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADFoxM1 →+0.355+2.820.012.03532
LUADp38-MAPK_pT180_Y182 →-0.602-3.000.001.03532
UCECFOXO3a_pS318_S321 →-0.145-2.990.035.03632
UCECVHL →-1.267-3.169<.001.02032
SKCMCaspase-8 →-0.107-1.700.048.04032
LUADBad_pS112 →-0.222-3.000.021.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

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