OR10Y1P

Across TCGA pan-cancer cohorts, OR10Y1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR10Y1P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR10Y1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR10Y1P is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

HNSC, BRCA, and KICH are the cancer types where OR10Y1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR10Y1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.272	<.001	12	view →
BRCA	Female	All	−0.060	<.001	6	view →
KICH	All	All	−0.027	.008	3	view →
COAD	All	II,III,IV	−0.032	.017	2	view →
KIRC	Male	IV	+0.090	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR10Y1P–HNSC

Open the HNSC breakdown →